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Listeria monocytogenes Mutants That Fail To Compartmentalize Listerolysin O Activity Are Cytotoxic, Avirulent, and Unable To Evade Host Extracellular Defenses

Listeria monocytogenes is a facultative intracellular bacterial pathogen that escapes from a phagosome and grows in the host cell cytosol. Escape of the bacterium from the phagosome to the cytosol is mediated by the bacterial pore-forming protein listeriolysin O (LLO). LLO has multiple mechanisms th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Glomski, Ian J., Decatur, Amy L., Portnoy, Daniel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC308949/
https://ncbi.nlm.nih.gov/pubmed/14638761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.6754-6765.2003
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