Listeria monocytogenes Mutants That Fail To Compartmentalize Listerolysin O Activity Are Cytotoxic, Avirulent, and Unable To Evade Host Extracellular Defenses

Listeria monocytogenes is a facultative intracellular bacterial pathogen that escapes from a phagosome and grows in the host cell cytosol. Escape of the bacterium from the phagosome to the cytosol is mediated by the bacterial pore-forming protein listeriolysin O (LLO). LLO has multiple mechanisms th...

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Pubblicato in:Infect Immun
Autori principali: Glomski, Ian J., Decatur, Amy L., Portnoy, Daniel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2003
Soggetti:
Bacterial Infections
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308949/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638761/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.12.6754-6765.2003
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