Haemophilus ducreyi Requires an Intact flp Gene Cluster for Virulence in Humans

An intact Haemophilus ducreyi flp operon is essential for microcolony formation in vitro. tadA is the 9th of 15 genes in the operon and has homology to NTPases of type IV secretion systems. Fifteen human volunteers were experimentally infected with both H. ducreyi 35000HP and the tadA mutant, 35000H...

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Main Authors: Spinola, Stanley M., Fortney, Kate R., Katz, Barry P., Latimer, Jo L., Mock, Jason R., Vakevainen, Merja, Hansen, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC308926/
https://ncbi.nlm.nih.gov/pubmed/14638812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7178-7182.2003
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