Attenuated Signature-Tagged Mutagenesis Mutants of Brucella melitensis Identified during the Acute Phase of Infection in Mice

For this study, we screened 1,152 signature-tagged mutagenesis mutants of Brucella melitensis 16M in a mouse model of infection and found 36 of them to be attenuated in vivo. Molecular characterization of transposon insertion sites showed that for four mutants, the affected genes were only present i...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lestrate, P., Dricot, A., Delrue, R.-M., Lambert, C., Martinelli, V., De Bolle, X., Letesson, J.-J., Tibor, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC308902/
https://ncbi.nlm.nih.gov/pubmed/14638795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7053-7060.2003
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky