Orally Administered CpG Oligodeoxynucleotide Induces Production of CXC and CC Chemokines in the Gastric Mucosa and Suppresses Bacterial Colonization in a Mouse Model of Helicobacter pylori Infection

Bacterial DNA and unmethylated CpG oligodeoxynucleotides (CpG ODN) are known to be potent stimulators of the innate immune system in vitro and in vivo. We therefore investigated if oral administration of CpG ODN could enhance innate immunity in the gastric mucosa and control the extent of Helicobact...

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Detalhes bibliográficos
Main Authors: Raghavan, S., Nyström, J., Fredriksson, M., Holmgren, J., Harandi, A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC308895/
https://ncbi.nlm.nih.gov/pubmed/14638791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7014-7022.2003
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