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Update on Aurora Kinase Targeted Therapeutics in Oncology
INTRODUCTION: Mammalian cells contain three distinct serine/threonine protein kinases with highly conserved catalytic domains, including aurora A and B kinases that are essential regulators of mitotic entry and progression. Overexpression of aurora A and/or B kinase is associated with high prolifera...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088914/ https://ncbi.nlm.nih.gov/pubmed/21556291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.2011.555395 |
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