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Mutation of putative N-Linked Glycosylation Sites in Japanese encephalitis Virus Premembrane and Envelope proteins enhances humoral immunity in BALB/C mice after DNA vaccination

Swine are an important host of Japanese encephalitis virus (JEV). The two membrane glycoproteins of JEV, prM and E, each contain a potential N-linked glycosylation site, at positions N15 and N154, respectively. We constructed plasmids that contain the genes encoding wild-type prME (contain the signa...

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Autores principales: Zhang, Yu, Chen, Puyan, Cao, Ruibing, Gu, Jinyan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088903/
https://ncbi.nlm.nih.gov/pubmed/21439032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-138
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