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DC-SIGN Binding Contributed by an Extra N-Linked Glycosylation on Japanese Encephalitis Virus Envelope Protein Reduces the Ability of Viral Brain Invasion

The major structural envelope (E) protein of Japanese encephalitis virus (JEV) facilitates cellular binding/entry and is the primary target of neutralizing antibodies. JEV E protein has one N-linked glycosylation site at N154 (G2 site), but the related dengue virus E protein has two glycosylation si...

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Udgivet i:Front Cell Infect Microbiol
Main Authors: Liang, Jian-Jong, Chou, Min-Wei, Lin, Yi-Ling
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048278/
https://ncbi.nlm.nih.gov/pubmed/30042931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00239
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