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Analysis of Virulence and Inflammatory Potential of Shigella flexneri Purine Biosynthesis Mutants
Several Shigella flexneri mutants with defects in aromatic amino acid and/or purine biosynthesis have been evaluated as vaccines in humans or in animal models. To be suitable as a vaccine, a mutant has to show virulence attenuation, minimal reactogenicity, and a good immunogenic potential in animal...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology
2003
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC308888/ https://ncbi.nlm.nih.gov/pubmed/14638790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7002-7013.2003 |
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