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Combinations of Protein-Chemical Complex Structures Reveal New Targets for Established Drugs

Biological networks are powerful tools for predicting undocumented relationships between molecules. The underlying principle is that existing interactions between molecules can be used to predict new interactions. Here we use this principle to suggest new protein-chemical interactions via the networ...

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Detalhes bibliográficos
Main Authors: Kalinina, Olga V., Wichmann, Oliver, Apic, Gordana, Russell, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088657/
https://ncbi.nlm.nih.gov/pubmed/21573205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002043
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