Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis

It is well-documented that the methylation of histone H3 lysine 4 (H3K4) and of H3K9 are mutually exclusive, an epigenetic phenomenon conserved from yeast to humans. How this opposed methylation modification is accomplished and coordinated in mammalian cells is poorly understood. Here we report that...

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Detalhes bibliográficos
Main Authors: Shi, Lei, Sun, Luyang, Li, Qian, Liang, Jing, Yu, Wenhua, Yi, Xia, Yang, Xiaohan, Li, Yanyan, Han, Xiao, Zhang, Yu, Xuan, Chenghao, Yao, Zhi, Shang, Yongfeng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088624/
https://ncbi.nlm.nih.gov/pubmed/21502505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017374108
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