CD4(+)CD25(+) regulatory T cells control CD8(+) T-cell effector differentiation by modulating IL-2 homeostasis

CD4(+)CD25(+) regulatory T cells (Treg) play a crucial role in the regulation of immune responses. Although many mechanisms of Treg suppression in vitro have been described, the mechanisms by which Treg modulate CD8(+) T cell differentiation and effector function in vivo are more poorly defined. It...

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Hlavní autoři: McNally, Alice, Hill, Geoffrey R., Sparwasser, Tim, Thomas, Ranjeny, Steptoe, Raymond J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088596/
https://ncbi.nlm.nih.gov/pubmed/21502514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103782108
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