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Immune escape from HIV-specific antibody-dependent cellular cytotoxicity (ADCC) pressure

Effective immunity to HIV is poorly understood. In particular, a role for antibody-dependent cellular cytotoxicity (ADCC) in controlling HIV is controversial. We hypothesized that significant pressure from HIV-specific ADCC would result in immune-escape variants. A series of ADCC epitopes in HIV-inf...

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Detalhes bibliográficos
Main Authors: Chung, Amy W., Isitman, Gamze, Navis, Marjon, Kramski, Marit, Center, Rob J., Kent, Stephen J., Stratov, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088575/
https://ncbi.nlm.nih.gov/pubmed/21502492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016048108
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