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Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development

The HIV-1 genome is malleable and a difficult target tot vaccinate against. It has long been recognised that cytotoxic T lymphocytes and neutralising antibodies readily select for immune escape HIV variants. It is now also clear that NK cells can also select for immune escape. NK cells force immune...

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Bibliografiska uppgifter
Huvudupphovsmän: Isitman, Gamze, Stratov, Ivan, Kent, Stephen J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350948/
https://ncbi.nlm.nih.gov/pubmed/22611395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/637208
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