A Selective Inhibitor of Drp1, Mdivi-1, Increases Retinal Ganglion Cell Survival in Acute Ischemic Mouse Retina

PURPOSE. To determine whether acute intraocular pressure (IOP) elevation alters dynamin-related protein 1 (Drp1) as well as whether a selective inhibitor of Drp1, mdivi-1, can block apoptotic cell death and subsequently increase retinal ganglion cell (RGC) survival in ischemic mouse retina. METHODS....

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Egile Nagusiak: Park, Sang Woo, Kim, Keun-Young, Lindsey, James D., Dai, Yi, Heo, Hwan, Nguyen, Duy H., Ellisman, Mark H., Weinreb, Robert N., Ju, Won-Kyu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Association for Research in Vision and Ophthalmology, Inc. 2011
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088566/
https://ncbi.nlm.nih.gov/pubmed/21372007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-5010
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