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TORC1 kinase and the S-phase cyclin Clb5 collaborate to promote mitotic spindle assembly and DNA replication in S. cerevisiae

The Target of Rapamycin complex 1 (TORC1) is a central regulator of eukaryotic cell growth that is inhibited by the drug rapamycin. In the budding yeast Saccharomyces cerevisiae, translational defects associated with TORC1 inactivation inhibit cell cycle progression at an early stage in G1, but litt...

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Hlavní autoři: Tran, Lieu T., Wang’ondu, Ruth W., Weng, Jessica B., Wanjiku, Grace W., Fong, Chi M., Kile, Andrew C., Koepp, Deanna M., Hood-DeGrenier, Jennifer K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088515/
https://ncbi.nlm.nih.gov/pubmed/20697716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-010-0316-0
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