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TORC1 kinase and the S-phase cyclin Clb5 collaborate to promote mitotic spindle assembly and DNA replication in S. cerevisiae

The Target of Rapamycin complex 1 (TORC1) is a central regulator of eukaryotic cell growth that is inhibited by the drug rapamycin. In the budding yeast Saccharomyces cerevisiae, translational defects associated with TORC1 inactivation inhibit cell cycle progression at an early stage in G1, but litt...

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書誌詳細
主要な著者: Tran, Lieu T., Wang’ondu, Ruth W., Weng, Jessica B., Wanjiku, Grace W., Fong, Chi M., Kile, Andrew C., Koepp, Deanna M., Hood-DeGrenier, Jennifer K.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088515/
https://ncbi.nlm.nih.gov/pubmed/20697716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-010-0316-0
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