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Mitochondria Are a Major Source of Paraquat-induced Reactive Oxygen Species Production in the Brain

Paraquat (PQ(2+)) is a prototypic toxin known to exert injurious effects through oxidative stress and bears a structural similarity to the Parkinson disease toxicant, 1-methyl-4-pheynlpyridinium. The cellular sources of PQ(2+)-induced reactive oxygen species (ROS) production, specifically in neurona...

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Bibliographische Detailangaben
Hauptverfasser: Castello, Pablo R., Drechsel, Derek A., Patel, Manisha
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088512/
https://ncbi.nlm.nih.gov/pubmed/17389593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700827200
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