Azole Resistance of Aspergillus fumigatus Biofilms Is Partly Associated with Efflux Pump Activity

This study investigated the phase-dependent expression and activity of efflux pumps in Aspergillus fumigatus treated with voriconazole. Fourteen strains were shown to become increasingly resistant in the 12-h (16- to 128-fold) and 24-h (>512-fold) phases compared to 8-h germlings. An Ala-Nap upta...

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Detalhes bibliográficos
Main Authors: Rajendran, Ranjith, Mowat, Eilidh, McCulloch, Elaine, Lappin, David F., Jones, Brian, Lang, Sue, Majithiya, Jayesh B., Warn, Peter, Williams, Craig, Ramage, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088214/
https://ncbi.nlm.nih.gov/pubmed/21321135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01189-10
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