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In Vitro and In Vivo Antiplasmodial Activities of Risedronate and Its Interference with Protein Prenylation in Plasmodium falciparum

The increasing resistance of malarial parasites to almost all available drugs calls for the identification of new compounds and the detection of novel targets. Here, we establish the antimalarial activities of risedronate, one of the most potent bisphosphonates clinically used to treat bone resorpti...

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Autores principales: Jordão, Fabiana Morandi, Saito, Alexandre Yukio, Miguel, Danilo Ciccone, de Jesus Peres, Valnice, Kimura, Emília Akemi, Katzin, Alejandro Miguel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088194/
https://ncbi.nlm.nih.gov/pubmed/21357292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01820-10
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