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Tomatidine Inhibits Replication of Staphylococcus aureus Small-Colony Variants in Cystic Fibrosis Airway Epithelial Cells

Small-colony variants (SCVs) often are associated with chronic Staphylococcus aureus infections, such as those encountered by cystic fibrosis (CF) patients. We report here that tomatidine, the aglycon form of the plant secondary metabolite tomatine, has a potent growth inhibitory activity against SC...

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Detalhes bibliográficos
Main Authors: Mitchell, Gabriel, Gattuso, Mariza, Grondin, Gilles, Marsault, Éric, Bouarab, Kamal, Malouin, François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088192/
https://ncbi.nlm.nih.gov/pubmed/21357296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01468-10
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