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Anthelmintics Are Substrates and Activators of Nematode P Glycoprotein
P glycoproteins (Pgp), members of the ABC transporter superfamily, play a major role in chemoresistance. In nematodes, Pgp are responsible for resistance to anthelmintics, suggesting that they are Pgp substrates, as they are in mammalian cells. However, their binding to nematode Pgp and the function...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088189/ https://ncbi.nlm.nih.gov/pubmed/21300828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01477-10 |
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