High Parasite Burdens Cause Liver Damage in Mice following Plasmodium berghei ANKA Infection Independently of CD8(+) T Cell-Mediated Immune Pathology

Infection of C57BL/6 mice with Plasmodium berghei ANKA induces a fatal neurological disease commonly referred to as experimental cerebral malaria. The onset of neurological symptoms and mortality depend on pathogenic CD8(+) T cells and elevated parasite burdens in the brain. Here we provide clear ev...

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Detalhes bibliográficos
Main Authors: Haque, Ashraful, Best, Shannon E., Amante, Fiona H., Ammerdorffer, Anne, de Labastida, Fabian, Pereira, Tamara, Ramm, Grant A., Engwerda, Christian R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088131/
https://ncbi.nlm.nih.gov/pubmed/21343349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01210-10
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