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Probing Intracellular Biomarkers and Mediators of Cell Activation Using Nanosensors and Bioorthogonal Chemistry

Nanomaterials offer unique physical properties that make them ideal biosensors for scant cell populations. However, specific targeting of nanoparticles to intracellular proteins has been challenging. Here, we describe a technique to improve intracellular biomarker sensing using nanoparticles that is...

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Bibliographic Details
Main Authors: Haun, Jered B., Devaraj, Neal K., Marinelli, Brett S., Lee, Hakho, Weissleder, Ralph
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088084/
https://ncbi.nlm.nih.gov/pubmed/21351804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn200333m
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