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A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors

Curcumin is a polyphenolic compound derived from the Indian spice turmeric. We used nanoparticle-encapsulated curcumin to treat medulloblastoma and glioblastoma cells. This formulation caused a dose-dependent decrease in growth of multiple brain tumor cell cultures, including the embryonal tumor der...

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Bibliographic Details
Main Authors: Lim, Kah Jing, Bisht, Savita, Bar, Eli E, Maitra, Anirban, Eberhart, Charles G
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087900/
https://ncbi.nlm.nih.gov/pubmed/21193839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.5.14410
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