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Alterations in Expression of HIF-1α, HIF-2α and VEGF by Idiopathic Overactive Bladder Urothelial Cells During Stretch Suggest a Role for Hypoxia

OBJECTIVES: Hypoxia has been theorized to play a role in overactive bladder (OAB) symptoms. This study was designed to test this hypothesis by studying how in vitro stretch of primary cultured bladder urothelial cells (BUC) from OAB subjects and asymptomatic subjects (NB) altered the expression of a...

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Detalhes bibliográficos
Main Authors: Christiaansen, Charlotte E., Sun, Yan, Hsu, Yu-chao, Chai, Toby C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087847/
https://ncbi.nlm.nih.gov/pubmed/21397301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2010.12.041
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