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Posttranslational Modification of 6-phosphofructo-1-kinase as an Important Feature of Cancer Metabolism

BACKGROUND: Human cancers consume larger amounts of glucose compared to normal tissues with most being converted and excreted as lactate despite abundant oxygen availability (Warburg effect). The underlying higher rate of glycolysis is therefore at the root of tumor formation and growth. Normal cont...

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Detalhes bibliográficos
Main Authors: Šmerc, Andreja, Sodja, Eva, Legiša, Matic
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087806/
https://ncbi.nlm.nih.gov/pubmed/21573193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019645
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