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Posttranslational Modification of 6-phosphofructo-1-kinase as an Important Feature of Cancer Metabolism

BACKGROUND: Human cancers consume larger amounts of glucose compared to normal tissues with most being converted and excreted as lactate despite abundant oxygen availability (Warburg effect). The underlying higher rate of glycolysis is therefore at the root of tumor formation and growth. Normal cont...

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Библиографические подробности
Главные авторы: Šmerc, Andreja, Sodja, Eva, Legiša, Matic
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087806/
https://ncbi.nlm.nih.gov/pubmed/21573193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019645
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