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Evolution of Allosteric Citrate Binding Sites on 6-phosphofructo-1-kinase

As an important part of metabolism, metabolic flux through the glycolytic pathway is tightly regulated. The most complex control is exerted on 6-phosphofructo-1-kinase (PFK1) level; this control overrules the regulatory role of other allosteric enzymes. Among other effectors, citrate has been report...

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Autores principales: Usenik, Aleksandra, Legiša, Matic
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990764/
https://ncbi.nlm.nih.gov/pubmed/21124851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015447
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