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Structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase in complex with the feedback inhibitor CoA reveals only one active-site conformation
Phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate step in the coenzyme A (CoA) biosynthetic pathway, reversibly transferring an adenylyl group from ATP to 4′-phosphopantetheine to form dephosphocoenzyme A (dPCoA). To complement recent biochemical and structural studies on Myco...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
International Union of Crystallography
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087636/ https://ncbi.nlm.nih.gov/pubmed/21543857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111010761 |
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