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TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA Activation

Many genetic and molecular alterations, such as K-ras mutation and NF-κB activation, have been identified in pancreatic cancer. However, the mechanisms by which pancreatic cancer metastasizes still remain to be determined. Although we previously showed that the tropomyosin-related kinase B (TrkB) wa...

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Detalhes bibliográficos
Main Authors: Li, Zhongkui, Chang, Zhe, Chiao, Lucia J., Kang, Ya’an, Xia, Qianghua, Zhu, Cihui, Fleming, Jason B., Evans, Douglas B., Chiao, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087630/
https://ncbi.nlm.nih.gov/pubmed/19773448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4002
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