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Correcting for cryptic relatedness by a regression-based genomic control method

BACKGROUND: Genomic control (GC) method is a useful tool to correct for the cryptic relatedness in population-based association studies. It was originally proposed for correcting for the variance inflation of Cochran-Armitage's additive trend test by using information from unlinked null markers...

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Autori principali: Yan, Ting, Hou, Bo, Yang, Yaning
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087514/
https://ncbi.nlm.nih.gov/pubmed/19954543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-10-78
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