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Atlas of Cryptic Genetic Relatedness Among 1000 Human Genomes

A novel computational method for detecting identical-by-descent (IBD) chromosomal segments between sequenced genomes is presented. It utilizes the distribution patterns of very rare genetic variants (vrGVs), which have minor allele frequencies <0.2%. Contrary to the existing probabilistic approac...

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Détails bibliographiques
Publié dans:Genome Biol Evol
Auteurs principaux: Fedorova, Larisa, Qiu, Shuhao, Dutta, Rajib, Fedorov, Alexei
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824066/
https://ncbi.nlm.nih.gov/pubmed/26907499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evw034
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