The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts

BACKGROUND: The proto-oncogene Src is an important non-receptor protein tyrosine kinase involved in signaling pathways that control cell adhesion, growth, migration and differentiation. It negatively regulates osteoblast activity, and, as such, its inhibition is a potential means to prevent bone los...

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Détails bibliographiques
Auteurs principaux: Id Boufker, Hichame, Lagneaux, Laurence, Najar, Mehdi, Piccart, Martine, Ghanem, Ghanem, Body, Jean-Jacques, Journé, Fabrice
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087319/
https://ncbi.nlm.nih.gov/pubmed/20565769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-298
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