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Hax1 regulates neutrophil adhesion and motility through RhoA

Kostmann disease is an inherited severe congenital neutropenia syndrome associated with loss-of-function mutations in an adaptor protein HS1-associated protein X-1 (Hax1). How Hax1 regulates neutrophil function remains largely unknown. In this paper, we use ribonucleic acid interference to deplete H...

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Bibliografiske detaljer
Main Authors: Cavnar, Peter J., Berthier, Erwin, Beebe, David J., Huttenlocher, Anna
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087009/
https://ncbi.nlm.nih.gov/pubmed/21518791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010143
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