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Differential regulation of protrusion and polarity by PI(3)K during neutrophil motility in live zebrafish

Cell polarity is crucial for directed migration. Here we show that phosphoinositide 3-kinase (PI(3)K) mediates neutrophil migration in vivo by differentially regulating cell protrusion and polarity. The dynamics of PI(3)K products PI(3,4,5)P(3)-PI(3,4)P(2) during neutrophil migration were visualized...

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Bibliografski detalji
Glavni autori: Yoo, Sa Kan, Deng, Qing, Cavnar, Peter J., Wu, Yi I., Hahn, Klaus M., Huttenlocher, Anna
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824622/
https://ncbi.nlm.nih.gov/pubmed/20159593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.11.015
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