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Differential regulation of protrusion and polarity by PI(3)K during neutrophil motility in live zebrafish
Cell polarity is crucial for directed migration. Here we show that phosphoinositide 3-kinase (PI(3)K) mediates neutrophil migration in vivo by differentially regulating cell protrusion and polarity. The dynamics of PI(3)K products PI(3,4,5)P(3)-PI(3,4)P(2) during neutrophil migration were visualized...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824622/ https://ncbi.nlm.nih.gov/pubmed/20159593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.11.015 |
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