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Mapping the Conformational Dynamics and Pathways of Spontaneous Steric Zipper Peptide Oligomerization

The process of protein misfolding and self-assembly into various, polymorphic aggregates is associated with a number of important neurodegenerative diseases. Only recently, crystal structures of several short peptides have provided detailed structural insights into [Image: see text]-sheet rich aggre...

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Hlavní autoři: Matthes, Dirk, Gapsys, Vytautas, Daebel, Venita, de Groot, Bert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086902/
https://ncbi.nlm.nih.gov/pubmed/21559277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019129
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