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Secondary Structure Propensities in Peptide Folding Simulations: A Systematic Comparison of Molecular Mechanics Interaction Schemes

We present a systematic study directed toward the secondary structure propensity and sampling behavior in peptide folding simulations with eight different molecular dynamics force-field variants in explicit solvent. We report on the combinational result of force field, water model, and electrostatic...

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Detalhes bibliográficos
Main Authors: Matthes, Dirk, de Groot, Bert L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711344/
https://ncbi.nlm.nih.gov/pubmed/19619475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.04.061
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