Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia and Decrease the Need for Ribavirin Dose Reduction

BACKGROUND & AIMS: In a genome-wide association study of patients being treated for chronic hepatitis C, 2 functional variants in ITPA that cause inosine triphosphatase (ITPase) deficiency were shown to protect against ribavirin (RBV)-induced hemolytic anemia during early stages of treatment. We...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Thompson, Alexander. J., Fellay, Jacques, Patel, Keyur, Tillmann, Hans L., Naggie, Susanna, Ge, Dongliang, Urban, Thomas J., Shianna, Kevin V., Muir, Andrew J., Fried, Michael W., Afdhal, Nezam H., Goldstein, David B., Mchutchison, John G.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086671/
https://ncbi.nlm.nih.gov/pubmed/20547162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.06.016
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items