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Synthesis of the Azaphilones (+)-Sclerotiorin and (+)-8-O-Methylsclerotiorinamine Utilizing (+)-Sparteine Surrogates in Copper-Mediated Oxidative Dearomatization

[Image: see text] Enantioselective syntheses of the azaphilone natural products (+)-sclerotiorin and (+)-8-O-methylsclerotiorinamine which possess the natural R-configuration at the quaternary center are reported. The syntheses were accomplished using copper-mediated asymmetric dearomatization emplo...

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Detalhes bibliográficos
Main Authors: Germain, Andrew R., Bruggemeyer, Daniel M., Zhu, Jianglong, Genet, Cedric, O’Brien, Peter, Porco, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086581/
https://ncbi.nlm.nih.gov/pubmed/21401026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo102448n
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