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A common telomeric gene silencing assay is affected by nucleotide metabolism
Telomere-associated position effect variegation (TPEV) in budding yeast has been used as a model for understanding epigenetic inheritance and gene silencing. A widely used assay to identify mutants with improper TPEV employs the URA3 gene at the telomere of chromosome VII-L that can be counter-selec...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086572/ https://ncbi.nlm.nih.gov/pubmed/21474074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.007 |
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