RSV-Induced Bronchial Epithelial Cell PD-L1 Expression Inhibits CD8(+) T Cell Nonspecific Antiviral Activity

Respiratory syncytial virus (RSV) is a major cause of bronchiolitis in infants. It is also responsible for high morbidity and mortality in the elderly. Programmed death ligands (PD-Ls) on antigen-presenting cells interact with receptors on T cells to regulate immune responses. The programmed death r...

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Detalhes bibliográficos
Main Authors: Telcian, Aurica G., Laza-Stanca, Vasile, Edwards, Michael R., Harker, James A., Wang, Hongwei, Bartlett, Nathan W., Mallia, Patrick, Zdrenghea, Mihnea T., Kebadze, Tatiana, Coyle, Anthony J., Openshaw, Peter J.M., Stanciu, Luminita A., Johnston, Sebastian L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086441/
https://ncbi.nlm.nih.gov/pubmed/21148500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq020
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