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Lipid Bilayer Molecular Dynamics Study of Lipid-Derived Agonists of the Putative Cannabinoid Receptor, GPR55

Both L-α-lysophosphatidylinositol (LPI) and 2-arachidonoyl-sn-glycero-3-phosphoinositol (2-AGPI) have been reported to activate the putative cannabinoid receptor, GPR55. Recent microsecond time-scale molecular dynamics (MD) simulations and isothiocyanate covalent labeling studies have suggested that...

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Autors principals: Kotsikorou, Evangelia, Lynch, Diane L., Abood, Mary E., Reggio, Patricia H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086297/
https://ncbi.nlm.nih.gov/pubmed/21185816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2010.12.003
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