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Regulatory T cells as therapeutic targets in rheumatoid arthritis

Regulatory T cells (T(REG)) are a subset of CD4(+) T cells with a critical role in the prevention of autoimmunity. Whether defects in T(REG) contribute to the pathogenesis of rheumatoid arthritis (RA) is unclear. However, a variety of approved and experimental drugs for RA may work, in part, by prom...

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Autors principals: Esensten, Jonathan H., Wofsy, David, Bluestone, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086064/
https://ncbi.nlm.nih.gov/pubmed/19798031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2009.183
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