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Seipin Is a Discrete Homooligomer
Seipin is a transmembrane protein that resides in the endoplasmic reticulum and concentrates at junctions between the ER and cytosolic lipid droplets. Mutations in the human seipin gene, including the missense mutation A212P, lead to congenital generalized lipodystrophy (CGL), characterized by the l...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086013/ https://ncbi.nlm.nih.gov/pubmed/21062080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1013003 |
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