N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-L-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis

Rheumatoid arthritis is associated with the development of autoantibodies to citrullinated self-proteins. Citrullinated synovial proteins, which are generated via the actions of the protein arginine deiminases (PADs), are known to develop in the murine collagen-induced arthritis (CIA) model of infla...

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Hlavní autoři: Willis, Van C., Gizinski, Alison M., Banda, Nirmal K., Causey, Corey P., Knuckley, Bryan, Cordova, Kristen N., Luo, Yuan, Levitt, Brandt, Glogowska, Magdalena, Chandra, Piyanka, Kulik, Liudmila, Robinson, William H., Arend, William P., Thompson, Paul R., Holers, V. Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085980/
https://ncbi.nlm.nih.gov/pubmed/21346230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001620
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