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Development of an orthotopic model of invasive pancreatic cancer in an immunocompetent murine host

PURPOSE: The most common preclinical models of pancreatic adenocarcinoma utilize human cells or tissues that are xenografted into immunodeficient hosts. Several immunocompetent, genetically engineered mouse models of pancreatic cancer exist; however, tumor latency and disease progression in these mo...

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Detalhes bibliográficos
Main Authors: Tseng, William W., Winer, Daniel, Kenkel, Justin A., Choi, Okmi, Shain, Alan H., Pollack, Jonathan R., French, Randy, Lowy, Andrew M., Engleman, Edgar G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085509/
https://ncbi.nlm.nih.gov/pubmed/20534740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2384
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