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Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking

Integrins are divalent cation-dependent, αβ heterodimeric adhesion receptors that control many fundamental aspects of cell behaviour by bi-directional signalling between the extracellular matrix and intracellular cytoskeleton. The activation state of cell surface integrins is tightly regulated by di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tiwari, Shweta, Askari, Janet A., Humphries, Martin J., Bulleid, Neil J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085436/
https://ncbi.nlm.nih.gov/pubmed/21511727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.084483
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