Biochemical and genetic analysis of butyrylcholinesterase (BChE) in a family, due to prolonged neuromuscular blockade after the use of succinylcholine

Butyrylcholinesterase (BChE) is a plasma enzyme that catalyzes the hydrolysis of choline esters, including the muscle-relaxant succinylcholine and mivacurium. Patients who present sustained neuromuscular blockade after using succinylcholine usually carry BChE variants with reduced enzyme activity or...

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Autores principales: Garcia, Daniel Fantozzi, Oliveira, Ticiano G., Molfetta, Greice A., Garcia, Luiz V., Ferreira, Cristiane A., Marques, Adriana A., Silva, Wilson Araujo
Formato: Artigo
Lenguaje:Inglês
Publicado: Sociedade Brasileira de Genética 2011
Materias:
Human and Medical Genetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085371/
https://ncbi.nlm.nih.gov/pubmed/21637541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572011000100008
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