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Adenovirus 12-mediated down-regulation of the major histocompatibility complex (MHC) class I promoter: identification of a negative regulatory element responsive to Ad12 E1A.

In highly oncogenic adenovirus (Ad) 12-transformed cells, major histocompatibility complex (MHC) class I gene expression is down-regulated by the products of the viral E1A oncogene at the level of initiation of transcription. However, class I gene expression is unaltered or elevated in non-oncogenic...

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Bibliografiska uppgifter
Huvudupphovsmän: Proffitt, J L, Sharma, E, Blair, G E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC308530/
https://ncbi.nlm.nih.gov/pubmed/7984430
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